James Briscoe is a senior group leader at The Francis Crick Institute. He obtained a B.Sc. in Microbiology and Virology from the University of Warwick, UK. Following a PhD in Ian Kerr’s laboratory at the Imperial Cancer Research Fund, London (now part of The Francis Crick Institute), he undertook postdoctoral training at Columbia University, New York, USA, with Thomas Jessell first as a Human Frontiers Science Program Fellow then as a Howard Hughes Medical Institute Fellow.
In 2000 he moved to the MRC-National Institute for Medical Research (now part of The Francis Crick Institute) to establish his own research group and in 2001 he was elected an EMBO Young Investigator. He was awarded the EMBO Gold Medal in 2008 and elected to EMBO in 2009. In 2012 he was appointed Head of Division in Developmental Biology. He serves on several Editorial Boards including PLoS Biology, Development and Developmental Biology. He is also a Director of the Company of Biologists where he chairs the Development Advisory Group and the Grants Committee.
His research interests include the molecular and cellular mechanisms of graded signalling by morphogens and the specification of cell fate in the vertebrate neural tube. To address these questions his lab uses a range of experimental and computational techniques and model systems that include mouse and chick embryos and embryonic stem cells.